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Posted Mon May 28 2012: from Public Library of Science :
New Type of Male Contraceptive?
A new type of male contraceptive could be created thanks to the discovery of a key gene essential for sperm development. The finding could lead to alternatives to the conventional male contraceptives that rely on disrupting the production of hormones, such as testosterone. These treatments can cause side-effects such as irritability, mood swings and acne. Research, led by the University of Edinburgh, has shown how a gene -- Katnal1 -- is critical to enable sperm to mature in the testes. If scientists can regulate the Katnal1 gene in the testes, they could prevent sperm from maturing completely, making them ineffective without changing hormone levels.
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